Cephalosporin Antibiotic

Preferred Label : Cephalosporin Antibiotic;

NCIt synonyms : Cephalosporins;

NCIt related terms : cephalosporin;

NCIt definition : A synthetic or semi-synthetic beta-lactam antibiotic derived from Acremonium (Cephalosporium) fungi with bactericidal activity. Cephalosporin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.;

Alternative definition : NCI-GLOSS: A drug used to treat bacterial infections. It belongs to the family of drugs called antibiotics.;

NCI Metathesaurus CUI : CL557638;

ChEBI ID : CHEBI:23066;

Codes from synonyms : CDR0000046676;

Details

Origin ID

C357;

UMLS CUI

C3536856;

Automatic exact mappings (from CISMeF team)
- Cephalosporins [ICHI extension code]
CISMeF manual mappings
- Antibiotic cephalosporin (group) [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Cephalosporin [LOINC component]
- Cephalosporin (substance) [SNOMED CT concept]
- Cephalosporins [ICD-11 Extension code]
- Substance with cephalosporin structure and antibacterial mechanism of action (substance) [SNOMED CT concept]
- cephalosporin [Substance BNPC]
- cephalosporin, nos [SNOMED Notion]
- cephalosporins [IUPAC Term]
- cephalosporins [MeSH Descriptor]
- cephalosporins [MeSH concept]
Manual NTBT mappings (CISMeF)
- Cephalosporins and other beta-lactam antibiotics [Bloc CIM-11]
See also inter- (CISMeF)
- Product containing cephalosporin and antibiotic (product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Cephalosporin [LOINC component]
- Product containing cephalosporin and antibiotic (product) [SNOMED CT concept]
- cephalosporin [Substance BNPC]
- cephalosporin, nos [SNOMED Notion]
- cephalosporins [MeSH concept]
- cephalosporins [MeSH Descriptor]
- cephalosporins [IUPAC Term]

Keyword's position in hierarchy(ies) :

Main resources

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