Homeobox Protein Nkx-2.8

Preferred Label : Homeobox Protein Nkx-2.8;

NCIt synonyms : NKX2H; Homeobox Protein-NK2 Homolog-H; NKX2-9; Homeobox Protein NK2 Homolog H; NK-2 Homolog 8; NK2 Transcription Factor Related Protein; NK-2 Homolog H; NKX2.8;

NCIt definition : Homeobox protein Nkx-2.8 (239 aa, 26 kDa) is encoded by the human NKX2-8 gene. This protein is involved in transcriptional regulation.;

NCIt note : Expressed in fetal liver by human NKX2H Gene (NK2 Homeobox Family), 239-aa 26-kDa Homeobox Protein NK2 Homolog H is a basic protein related to nk-2 (Drosophila) homeobox transcription factor containing a homeobox domain and a conserved peptide of nk-2-related proteins. A likely component of PCF (an AFP developmental regulator), NKX2H binds to the AFP gene promoter-linked coupling element (PCE) and activates transcription.;

Details

Origin ID

C33971;

UMLS CUI

C1334041;

OMIM relation
- Nk2 homeobox 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- NKX2-8 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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