Actinic Keratosis

Preferred Label : Actinic Keratosis;

NCIt synonyms : Senile Hyperkeratosis; Senile Keratosis; Actinic Solar Keratosis; AK;

NCIt related terms : solar keratosis; Actinic (Solar) Keratosis;

NCIt definition : A precancerous lesion of the skin composed of atypical keratinocytes. It is characterized by the presence of thick, scaly patches of skin. Several histologic variants have been described, including atrophic, acantholytic, hypertrophic, proliferative, lichenoid, bowenoid, and pigmented variants.;

Alternative definition : NCI-GLOSS: A thick, scaly patch of skin that may become cancer. It usually forms on areas exposed to the sun, such as the face, scalp, back of the hands, or chest. It is most common in people with fair skin.;

Neoplastic status : Precancerous;

Codes from synonyms : CDR0000045133; CDR0000044480; CDR0000044479;

Details

Origin ID

C3148;

UMLS CUI

C0022602;

Automatic exact mappings (from CISMeF team)
- Actinic cheilitis (disorder) [SNOMED CT concept]
- Actinic keratosis [ICD-9 code]
- Senile hyperkeratosis (disorder) [SNOMED CT concept]
- Solar keratosis [PASCAL descriptor]
- skin cancer [MedlinePlus Topic]
- sun exposure [MedlinePlus Topic]
Currated CISMeF NLP mapping
- Actinic keratosis [PASCAL descriptor]
- Actinic keratosis [ICD-10 Sub-category]
- Actinic keratosis [HPO term]
- Actinic keratosis [ICD-11 Subcategory]
- Actinic keratosis [ICD-11 Extension code]
- Actinic keratosis [ICD-10 Sub-category (who)]
- Actinic keratosis [MedDRA Preferred Term]
- Actinic keratosis (disorder) [SNOMED CT concept]
- Actinic keratosis (morphologic abnormality) [SNOMED CT concept]
- Solar keratosis [MedDRA LLT]
- actinic keratosis [DO Concept]
- actinic keratosis [Disease (Nov.)]
- actinic keratosis [SNOMED Notion]
- keratosis, actinic [MeSH Descriptor]
- keratosis, actinic [MeSH concept]
DO Cross reference
- actinic keratosis [DO Concept]
Disease may have findings
- Parakeratosis [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Actinic keratosis [ICD-9 code]
- Actinic keratosis [ICD-10 Sub-category]
- Actinic keratosis [PASCAL descriptor]
- Actinic keratosis [HPO term]
- Actinic keratosis [ICD-11 Subcategory]
- Actinic keratosis [ICD-10 Sub-category (who)]
- Actinic keratosis [MedDRA Preferred Term]
- Actinic keratosis (disorder) [SNOMED CT concept]
- Actinic keratosis (morphologic abnormality) [SNOMED CT concept]
- Senile keratoma [MedDRA LLT]
- Senile keratoma (disorder) [SNOMED CT concept]
- Senile keratosis [MedDRA LLT]
- Solar keratosis [MedDRA LLT]
- actinic keratosis [DO Concept]
- actinic keratosis [Disease (Nov.)]
- actinic keratosis [SNOMED Notion]
- keratosis, actinic [MeSH concept]
- keratosis, actinic [MeSH Descriptor]
Validated automatic mappings to BTNT
- Senile keratosis [MedDRA LLT]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Full-Thickness Epidermal Atypia [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Keratinocyte [NCIt concept]
disease_has_associated_disease
- Desmoplastic Melanoma [NCIt concept]
- Desmoplastic Neurotropic Melanoma [NCIt concept]
- High-CSD Melanoma [NCIt concept]
- Lentigo Maligna Melanoma [NCIt concept]
- Melanoma in Chronically Sun-Exposed Skin [NCIt concept]
- Pleomorphic Dermal Sarcoma [NCIt concept]
- Recurrent Lentigo Maligna Melanoma [NCIt concept]
- Stage I Lentigo Maligna Melanoma AJCC v7 [NCIt concept]
- Stage II Lentigo Maligna Melanoma AJCC v6 and v7 [NCIt concept]
- Stage III Lentigo Maligna Melanoma AJCC v7 [NCIt concept]
- Stage IV Lentigo Maligna Melanoma AJCC v6 and v7 [NCIt concept]
disease_has_finding
- Absence of Invasion [NCIt concept]
- Atypia [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Dysplasia [NCIt concept]
- Hyperkeratosis [NCIt concept]
disease_has_normal_cell_origin
- Keratinocyte [NCIt concept]
disease_has_normal_tissue_origin
- Epidermis [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]
- Sun-exposed Site [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Mutation [NCIt concept]
- CDKN2B Gene Mutation [NCIt concept]
- FAT1 Gene Mutation [NCIt concept]
- NOTCH1 Gene Mutation [NCIt concept]
- NOTCH2 Gene Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]
may_be_associated_disease_of_disease
- Atypical Fibroxanthoma [NCIt concept]
- Classic Atypical Fibroxanthoma [NCIt concept]
- Clear Cell Atypical Fibroxanthoma [NCIt concept]
- Granular Cell Atypical Fibroxanthoma [NCIt concept]
- Keloidal Atypical Fibroxanthoma [NCIt concept]
- Myxoid Atypical Fibroxanthoma [NCIt concept]
- Pigmented Atypical Fibroxanthoma [NCIt concept]
- Pseudoangiomatous Atypical Fibroxanthoma [NCIt concept]
- Spindle Cell Atypical Fibroxanthoma [NCIt concept]

Keyword's position in hierarchy(ies) :

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