Castleman Disease

Preferred Label : Castleman Disease;

NCIt synonyms : Angiofollicular Lymphoid Hyperplasia; Giant Lymph Node Hyperplasia; Castleman's Tumor; Castleman's Disease; AFLH; GLNH;

NCIt definition : A disorder characterized by lymphoid hyperplasia in the lymph nodes. There are two histologic variants recognized: the hyaline-vascular type and the plasma cell type. In the hyaline vascular type there are hyalinized vessels present in the lymphoid follicles. In the plasma cell type there is pronounced plasma cell proliferation. Clinically, the disease may be localized; manifested with localized lymphadenopathy, or multicentric; manifested with generalized lymphadenopathy, fever, organomegaly, and sometimes POEMS syndrome. In contrast to patients with localized disease who are usually cured following resection of the lesion, patients with the multicentric form of the disease may follow a progressive clinical course, complicated by infection, Kaposi sarcoma or lymphoma.;

Alternative definition : NCI-GLOSS: A rare disorder in which growths that are benign (not cancer) develop in lymph node tissue.;

Codes from synonyms : CDR0000046043;

Details

Origin ID

C3056;

UMLS CUI

C0017531;

Automatic exact mappings (from CISMeF team)
- Adenolymphoma (disorder) [SNOMED CT concept]
- Adenolymphoma (morphologic abnormality) [SNOMED CT concept]
- Askin tumor (morphologic abnormality) [SNOMED CT concept]
- Askin's tumor [MedDRA LLT]
- B-cell type acute leukaemia [MedDRA Preferred Term]
- Burkitt lymphoma (morphologic abnormality) [SNOMED CT concept]
- Burkitt's lymphoma (disorder) [SNOMED CT concept]
- Burkitt's tumor [MedDRA LLT]
- Castleman disease [Radlex concept]
- Chondroblastoma (morphologic abnormality) [SNOMED CT concept]
- Eccrine dermal cylindroma of skin (disorder) [SNOMED CT concept]
- Ewing's sarcoma [MedDRA Preferred Term]
- Ewing's sarcoma (morphologic abnormality) [SNOMED CT concept]
- Ewing's tumor [MedDRA LLT]
- Granular cell tumor (disorder) [SNOMED CT concept]
- Juvenile aponeurotic fibroma (morphologic abnormality) [SNOMED CT concept]
- Klatskin Tumor [MeSH Descriptor]
- Klatskin's tumor (disorder) [SNOMED CT concept]
- Klatskin's tumor (morphologic abnormality) [SNOMED CT concept]
- Nephroblastoma [HPO term]
- Pancoast's tumor [MedDRA LLT]
- Pancoast's tumour [MedDRA Preferred Term]
- Papillary intralymphatic angioendothelioma of childhood (disorder) [SNOMED CT concept]
- Small cell sarcoma (morphologic abnormality) [SNOMED CT concept]
- Trichoepithelioma (disorder) [SNOMED CT concept]
- Trichoepithelioma (morphologic abnormality) [SNOMED CT concept]
- Ungual fibroma [HPO term]
- Warthin's tumor [MedDRA LLT]
- abrikosov's tumor [MeSH concept]
- abrikosov's tumor [MeSH Supplementary Concept]
- burkitt lymphoma [MeSH Descriptor]
- klatskin's tumor [SNOMED Notion]
- krukenberg tumor [MeSH Descriptor]
- sarcoma, ewing [MeSH Descriptor]
- wilms tumor [MeSH Descriptor]
Currated CISMeF NLP mapping
- Castleman Disease [MeSH Descriptor]
- Castleman Disease [MeSH concept]
- Castleman disease [PASCAL descriptor]
- Castleman disease [DO Concept]
- Castleman disease [Vue CIM-11]
- Castleman disease [ORDO Disease]
- Castleman's disease [MedDRA Preferred Term]
- Castleman's disease (disorder) [SNOMED CT concept]
- Giant lymph node hyperplasia (disorder) [SNOMED CT concept]
- angiofollicular lymph node hyperplasia [Disease (Nov.)]
- angiolymphoid hyperplasia [SNOMED Notion]
DO Cross reference
- Castleman disease [DO Concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
Disease may have findings
- Interleukin-6 Overexpression [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Angiofollicular lymph node hyperplasia (morphologic abnormality) [SNOMED CT concept]
- Castleman Disease [MeSH concept]
- Castleman Disease [MeSH Descriptor]
- Castleman disease [ORDO Disease]
- Castleman disease [Radlex concept]
- Castleman's disease [MedDRA Preferred Term]
- Castleman's disease (disorder) [SNOMED CT concept]
- Giant lymph node hyperplasia (disorder) [SNOMED CT concept]
- angiofollicular lymph node hyperplasia [Disease (Nov.)]
disease_has_abnormal_cell
- Abnormal Hematopoietic and Lymphoid Cell [NCIt concept]
- Abnormal Lymphocyte [NCIt concept]
- Atypical Lymphocyte [NCIt concept]
disease_has_finding
- Lymphoplasmacytic Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
may_be_associated_disease_of_disease
- Chordoid Meningioma [NCIt concept]
- Conventional Follicular Dendritic Cell Sarcoma [NCIt concept]
- EBV-Positive Inflammatory Follicular Dendritic Cell/Fibroblastic Reticular Cell Tumor [NCIt concept]
- EBV-Positive Inflammatory Follicular Dendritic Cell/Fibroblastic Reticular Cell Tumor of the Digestive System [NCIt concept]
- Follicular Dendritic Cell Sarcoma [NCIt concept]
- Glomeruloid Hemangioma [NCIt concept]
- Head and Neck Follicular Dendritic Cell Sarcoma [NCIt concept]
- Mediastinal Follicular Dendritic Cell Sarcoma [NCIt concept]
- Thyroid Gland Follicular Dendritic Cell Sarcoma [NCIt concept]

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