Cytokine SCM-1 Beta

Preferred Label : Cytokine SCM-1 Beta;

NCIt synonyms : SCM1B; Small Inducible Cytokine C2; SCYC2; Small Inducible Cytokine Subfamily C Member 2; XC Chemokine Ligand 2; XCL2; C Motif Chemokine 2; Chemokine (C Motif) Ligand 2; C Motif Chemokine Ligand-2; Single Cysteine Motif 1B; Small-Inducible Cytokine C2;

NCIt definition : Cytokine SCM-1 beta (114 aa, 13 kDa) is encoded by the human XCL2 gene. This protein plays a role in lymphocyte chemotaxis.;

NCIt note : The amino acid sequences for lymphotactin and cytokine SCM-1 beta are identical except for 2 residues. The amino acids at positions 7 and 8 of lymphotactin are aspartic acid followed by lysine while in cytokine SCM-1 beta those positions house histidine followed by arginine.;

Details

Origin ID

C30153;

UMLS CUI

C1332831;

Automatic exact mappings (from CISMeF team)
- Chemokine, C motif, ligand 2 [OMIM gene]
- XCL-2 calpain [MeSH Supplementary Concept]
OMIM relation
- Chemokine, C motif, ligand 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- XCL2 protein, human [MeSH Supplementary Concept]
- XCL2 protein, human [MeSH concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- XCL2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Central Nervous System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chemotactic Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Maturation [NCIt concept]

Keyword's position in hierarchy(ies) :

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