Paired Box Protein Pax-5

Preferred Label : Paired Box Protein Pax-5;

NCIt synonyms : B-Cell Specific Transcription Factor; B-Cell Lineage Specific Activator Protein; Paired Box Homeotic Gene 5; PAX5; Paired Box 5; BSAP; Paired Box-5 Protein; B-Cell-Specific Transcription Factor;

NCIt definition : Paired box protein Pax-5 (391 aa, 42 kDa) is encoded by the human PAX5 gene. This protein plays a role in B-cell differentiation, neural development, spermatogenesis and gene transcription.;

Details

Origin ID

C30124;

UMLS CUI

C1527583;

OMIM relation
- Paired box gene 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- PAX5 protein, human [MeSH Supplementary Concept]
- PAX5 protein, human [MeSH concept]
gene_encodes_gene_product
- PAX5 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Transcription Coactivator [NCIt concept]
gene_product_has_gene_product_variant
- PAX5 NP_057953.1:p.A322T [NCIt concept]
- PAX5 NP_057953.1:p.G183S [NCIt concept]
- PAX5 NP_057953.1:p.P80R [NCIt concept]
- PAX5 Protein Variant [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_malfunction_associated_with_disease
- Small Lymphocytic Lymphoma [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Activation [NCIt concept]
- DNA Binding [NCIt concept]
- Neural Development [NCIt concept]
- Spermatogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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