Protein Lyl-1 - CISMeF

Preferred Label : Protein Lyl-1;

NCIt synonyms : Lyl-1 Protein; LYL1; bHLHa18; Class A Basic Helix-Loop-Helix Protein 18; Lymphoblastic Leukemia Derived Sequence 1; LYL1 Protein;

NCIt definition : Protein lyl-1 (280 aa, 30 kDa) is encoded by the human LYL1 gene. This protein is involved in blood vessel maturation and transcriptional regulation.;

NCIt note : Efficient DNA binding of this protein requires dimerization with another bHLH protein.;

Details

Origin ID

C30097;

UMLS CUI

C1334355;

OMIM relation
- Lymphoblastic leukemia-derived sequence 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LYL1 protein, human [MeSH concept]
- LYL1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- LYL1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_malfunction_associated_with_disease
- Acute Lymphoblastic Leukemia [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- DNA Binding [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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