NCIt definition : A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium
bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although
the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine
likely activates a Th1 cytokine response that includes the induction of interferon.
Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium
tuberculosis.;
Alternative definition : NICHD: A tuberculosis vaccine containing bacillus Calmette-Guérin, a live attenuated
strain of Mycobacterium bovis. There are many different strains of BCG vaccine, all
of which were originally derived from one strain, but which now have very different
properties.; NCI-GLOSS: A weakened form of the bacterium Mycobacterium bovis (bacillus Calmette-Guerin)
that does not cause disease. BCG is used in a solution to stimulate the immune system
in the treatment of bladder cancer and as a vaccine to prevent tuberculosis.;
Drug name : Monovax; TICE BCG; Pacis; Pastimmun; ImmuCyst; Imovax BCG; Cultivo BCG; Oncotice;
NSC code : 116328; 116341; 614389;
Codes from synonyms : CDR0000044581; NSC0007817; NSC0614388; CDR0000045987; 00495; 59;