R-Spondin-3 - CISMeF

Preferred Label : R-Spondin-3;

NCIt synonyms : THSD2; R-Spondin 3 Homolog; Thrombospondin Type-1 Domain-Containing Protein 2; Thrombospondin Type-I Domain-2 Protein; Protein with TSP Type-1 Repeat; hRspo3; Thrombospondin Type I Domain 2 Protein; Roof Plate-Specific Spondin-3; hPWTSR;

NCIt definition : R-spondin-3 (272 aa, 31 kDa) is encoded by the human RSPO3 gene. This protein is involved in the modulation of the canonical Wnt signaling pathway.;

NCIt note : R-spondin-3 contains a furin-like cysteine-rich region and is similar to thrombospondin type 1 domain-containing proteins.;

Details

Origin ID

C29579;

UMLS CUI

C1259459;

OMIM relation
- R-spondin 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RSPO3 protein, human [MeSH concept]
- RSPO3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RSPO3 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Heparin Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Rosmantuzumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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