rF-PSA/PSMA/TRICOM

Preferred Label : rF-PSA/PSMA/TRICOM;

NCIt synonyms : rF-PSA PSMA TRICOM;

NCIt definition : A synthetic fowlpox viral vaccine containing the tumor-associated antigens prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM). Vaccination with this viral vaccine may enhance antigen presentation and activate cytotoxic T-cells against PSA- or PSMA-expressing tumor cells.;

NSC code : 711153;

Details

Origin ID

C29559;

UMLS CUI

C1515685;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Gene Regulation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
has_target
- Glutamate Carboxypeptidase 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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