Preferred Label : Skin Basal Cell Carcinoma;
NCIt synonyms : Basal Cell Skin Carcinoma; Basal Cell Carcinoma of Skin; Basal Cell Cancer; BCC; Basal Cell Epithelioma; Basal Cell Carcinoma of the Skin;
NCIt related terms : Basal Cell Carcinoma; Skin Basal Cell Cancer;
NCIt definition : The most frequently seen skin cancer. It arises from basal cells of the epidermis
and pilosebaceous units. Clinically it is divided into the following types: nodular,
ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like.
More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing
skin, most commonly on sun-exposed areas. Approximately 85% are found on the head
and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma
usually grows in a slow and indolent fashion. However, if untreated, the tumor may
invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare.
Excision, curettage and irradiation cure most basal cell carcinomas.;
Alternative definition : NCI-GLOSS: Cancer that begins in the lower part of the epidermis (the outer layer
of the skin). It may appear as a small white or flesh-colored bump that grows slowly
and may bleed. Basal cell cancers are usually found on areas of the body exposed to
the sun. Basal cell cancers rarely metastasize (spread) to other parts of the body.
They are the most common form of skin cancer.;
Neoplastic status : Malignant;
ICD-O code : 8090/3;
Codes from synonyms : CDR0000046515; CDR0000667109; 10004146;
Origin ID : C2921;
UMLS CUI : C4721806;
Automatic exact mappings (from CISMeF team)
- Disease excludes abnormal cell
- Excludes anatomical site(s)
- HPO term
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- Validated automatic mappings to NTBT
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_associated_disease
- disease_has_associated_gene
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_mapped_to_gene
- disease_may_have_molecular_abnormality
- may_be_associated_disease_of_disease
- pathogenesis_of_disease_involves_gene
