Irbesartan - CISMeF

Preferred Label : Irbesartan;

NCIt definition : A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI05);

UNII : J0E2756Z7N;

CAS number : 138402-11-6;

Drug name : Avapro;

Chemical formula : C25H28N6O;

ChEBI ID : CHEBI:5959;

Codes from synonyms : 32061;

Details

Origin ID

C29130;

UMLS CUI

C0288171;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Irbesartan [MeSH Descriptor]
- Irbesartan [LOINC component]
- Irbesartan (substance) [SNOMED CT concept]
- Product containing irbesartan (medicinal product) [SNOMED CT concept]
- irbesartan [ATC Code]
- irbesartan [Substance BNPC]
- irbesartan [MeSH concept]
Validated automatic mappings to BTNT
- irbesartan [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2C9 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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