Preferred Label : Irbesartan;

MeSH definition : A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.;

MeSH hyponym : SR-47436; SR47436; BMS-186295;

MeSH CAS label : 1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-;

MeSH Related Number : 138402-11-6 (Irbesartan);

UNII : J0E2756Z7N;

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A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.

https://www.has-sante.fr/jcms/p_3215573/fr/aprexevo
2020
false
false
false
France
insurance, health, reimbursement
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Irbesartan
amlodipine
irbesartan and amlodipine
hypertension
adult
antihypertensive agents
calcium channel blockers
angiotensin II type 1 receptor blockers
guidelines for drug use
evaluation of the transparency committee

---
https://www.ansm.sante.fr/actualites/rappel-de-lots-de-medicaments-a-base-dirbesartan
2019
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false
false
France
French
drug contamination
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diethylnitrosamine
Safety-Based drug withdrawals
pharmacovigilance note
hotlines
biphenyl compounds
tetrazoles
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69617954
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66489392
2012
France
summary of product characteristics
package leaflet
tablets
france
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67278957
2012
France
summary of product characteristics
package leaflet
france
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64102929
2012
France
summary of product characteristics
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tablets
france
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68041434
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68973207
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66049051
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69261682
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66537862
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62875368
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68417018
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63462842
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68121332
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68352481
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60519505
2012
France
summary of product characteristics
package leaflet
health
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66802809
2012
France
summary of product characteristics
package leaflet
health
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69985835
2012
France
summary of product characteristics
package leaflet
tablets
health
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69464768
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60075598
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=62962549
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=63088184
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64578682
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68001564
2012
France
package leaflet
summary of product characteristics
tablets
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Karvezide
2012
United Kingdom
French
English
syndication feed
hypertension
biphenyl compounds
biphenyl compounds
tetrazoles
tetrazoles
angiotensin II type 1 receptor blockers
angiotensin II type 1 receptor blockers
antihypertensive agents
antihypertensive agents
hydrochlorothiazide
hydrochlorothiazide
diuretics
diuretics
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irbesartan and diuretics
biphenyl compounds
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summary of product characteristics
package leaflet
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Karvea
2012
United Kingdom
French
English
syndication feed
biphenyl compounds
hypertension
biphenyl compounds
tetrazoles
tetrazoles
antihypertensive agents
antihypertensive agents
angiotensin II type 1 receptor blockers
angiotensin II type 1 receptor blockers
pregnancy
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drug approval
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tablets
drug interactions
diabetic nephropathies
irbesartan
biphenyl compounds
tetrazoles
drug evaluation
summary of product characteristics
package leaflet
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/CoAprovel
2012
United Kingdom
English
French
syndication feed
biphenyl compounds
biphenyl compounds
tetrazoles
tetrazoles
angiotensin II type 1 receptor blockers
angiotensin II type 1 receptor blockers
antihypertensive agents
antihypertensive agents
hydrochlorothiazide
hydrochlorothiazide
diuretics
diuretics
adult
treatment outcome
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hypertension
tablets
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drug evaluation, preclinical
irbesartan and diuretics
biphenyl compounds
tetrazoles
drug evaluation
summary of product characteristics
package leaflet
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Aprovel
2012
United Kingdom
French
English
syndication feed
hypertension
adult
pregnancy
breast feeding
antihypertensive agents
antihypertensive agents
biphenyl compounds
biphenyl compounds
angiotensin II type 1 receptor blockers
angiotensin II type 1 receptor blockers
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tablets
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drug interactions
diabetic nephropathies
irbesartan
biphenyl compounds
drug evaluation
summary of product characteristics
package leaflet
Irbesartan
Irbesartan
tetrazoles
tetrazoles

---
https://www.ema.europa.eu/medicines/human/EPAR/irbesartan-hydrochlorothiazide-zentiva-previously-irbesartan-hydrochlorothiazide-winthrop
2012
false
United Kingdom
French
English
syndication feed
biphenyl compounds
tetrazoles
angiotensin II type 1 receptor blockers
antihypertensive agents
hydrochlorothiazide
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hypertension
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tetrazoles
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antihypertensive agents
hydrochlorothiazide
diuretics
adult
pregnancy
breast feeding
drug evaluation
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drug labeling
drug approval
drug combinations
tablets
drug interactions
drug evaluation, preclinical
irbesartan and diuretics
biphenyl compounds
tetrazoles
drug evaluation
package leaflet
summary of product characteristics
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/irbesartan-zentiva-previously-irbesartan-winthrop
2012
false
United Kingdom
English
French
syndication feed
angiotensin II type 1 receptor blockers
biphenyl compounds
tetrazoles
antihypertensive agents
hypertension
adult
biphenyl compounds
tetrazoles
angiotensin II type 1 receptor blockers
antihypertensive agents
pregnancy
breast feeding
tablets
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drug approval
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drug labeling
diabetic nephropathies
irbesartan
biphenyl compounds
tetrazoles
summary of product characteristics
package leaflet
drug evaluation
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Sabervel
2012
United Kingdom
French
English
summary of product characteristics
drug evaluation
package leaflet
syndication feed
drug approval
treatment outcome
administration, oral
irbesartan
biphenyl compounds
biphenyl compounds
tetrazoles
tetrazoles
Product containing precisely irbesartan 75 milligram/1 each conventional release oral tablet (clinical drug)
Product containing precisely irbesartan 150 milligram/1 each conventional release oral tablet (clinical drug)
Product containing precisely irbesartan 300 milligram/1 each conventional release oral tablet (clinical drug)
antihypertensive agents
antihypertensive agents
angiotensin II type 1 receptor blockers
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hypertension
adult
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pregnancy
breast feeding
Irbesartan
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68041612
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=69648202
2012
France
summary of product characteristics
package leaflet
tablets
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Ifirmacombi
2012
false
United Kingdom
French
English
syndication feed
hydrochlorothiazide
drug combinations
hydrochlorothiazide
antihypertensive agents
antihypertensive agents
angiotensin II type 1 receptor blockers
angiotensin II type 1 receptor blockers
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summary of product characteristics
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drug evaluation
Irbesartan
Irbesartan
biphenyl compounds
biphenyl compounds
tetrazoles
tetrazoles

---
https://www.ema.europa.eu/medicines/human/EPAR/irbesartanhydrochlorothiazide-teva
2012
false
United Kingdom
French
English
syndication feed
drug approval
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drug labeling
drug interactions
pregnancy
biphenyl compounds
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tetrazoles
tetrazoles
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adult
breast feeding
sodium chloride symporter inhibitors
sodium chloride symporter inhibitors
drug evaluation, preclinical
biphenyl compounds
tetrazoles
drug evaluation
package leaflet
summary of product characteristics
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Irbesartan-Teva
2012
United Kingdom
French
English
syndication feed
angiotensin II type 1 receptor blockers
biphenyl compounds
tetrazoles
antihypertensive agents
irbesartan
angiotensin II type 1 receptor blockers
biphenyl compounds
tetrazoles
antihypertensive agents
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drug labeling
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aged
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administration, oral
diabetic nephropathies
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pregnancy
breast feeding
drug evaluation, preclinical
biphenyl compounds
tetrazoles
summary of product characteristics
drug evaluation
package leaflet
Irbesartan
Irbesartan

---
http://www.has-sante.fr/portail/display.jsp?id=c_532065
http://www.has-sante.fr/portail/jcms/c_1323134/coaprovel
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-10/coaprovel_03102012_avis_ct12427.pdf
2012
France
French
drug combinations
sodium chloride symporter inhibitors
antihypertensive agents
diuretics
hydrochlorothiazide
angiotensin II type 1 receptor blockers
irbesartan and diuretics
hypertension
adult
administration, oral
insurance, health, reimbursement
evaluation of the transparency committee
Irbesartan
biphenyl compounds
tetrazoles

---
https://www.ema.europa.eu/medicines/human/EPAR/ifirmasta-previously-irbesartan-krka
2011
false
United Kingdom
French
English
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angiotensin II type 1 receptor blockers
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tetrazoles
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angiotensin II type 1 receptor blockers
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aged
diabetic nephropathies
irbesartan
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Irbesartan
Irbesartan

---
http://www.lecrat.eu/?s=Irb%C3%A9sartan+-+APROVEL%C2%AE
2011
France
French
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angiotensin II type 1 receptor blockers
angiotensin II type 1 receptor blockers
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teratogens
antihypertensive agents
antihypertensive agents
irbesartan
biphenyl compounds
biphenyl compounds
drug information
Contraindications, Drug
Irbesartan
tetrazoles
tetrazoles
tetrazoles

---
https://www.ema.europa.eu/medicines/human/EPAR/Irbesartan-Hydrochlorothiazide-BMS
2009
United Kingdom
French
English
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biphenyl compounds
tetrazoles
antihypertensive agents
angiotensin II type 1 receptor blockers
hydrochlorothiazide
diuretics
hypertension
tetrazoles
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drug interactions
drug evaluation, preclinical
irbesartan and diuretics
biphenyl compounds
biphenyl compounds
tetrazoles
drug evaluation
package leaflet
summary of product characteristics
Irbesartan
Irbesartan

---
https://www.ema.europa.eu/medicines/human/EPAR/Irbesartan-BMS
2009
United Kingdom
English
French
syndication feed
biphenyl compounds
tetrazoles
antihypertensive agents
angiotensin II type 1 receptor blockers
hypertension
adult
biphenyl compounds
tetrazoles
antihypertensive agents
angiotensin II type 1 receptor blockers
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breast feeding
tablets
drug evaluation
treatment outcome
drug approval
drug labeling
aged
drug interactions
diabetic nephropathies
drug evaluation, preclinical
irbesartan
biphenyl compounds
tetrazoles
drug evaluation
summary of product characteristics
package leaflet
Irbesartan
Irbesartan

---
https://www.minerva-ebp.be/fr/article/852
2005
false
false
minerva-ebm.be
Belgium
French
diabetes complications
angiotensin II type 1 receptor blockers
cardiovascular diseases
diabetes mellitus, type 2
treatment outcome
amlodipine
calcium channel blockers
placebos
diabetic nephropathies
biphenyl compounds
tetrazoles
antihypertensive agents
biphenyl compounds
tetrazoles
Amlodipine Besylate
critical appraisal or critical reading
comparative study
Irbesartan

---
http://www.has-sante.fr/portail/jcms/c_1322224/aprovel
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-10/aprovel_03102012_avis_ct12428.pdf
http://www.has-sante.fr/portail/display.jsp?id=c_400689
2005
France
French
biphenyl compounds
tetrazoles
angiotensin II type 1 receptor blockers
administration, oral
antihypertensive agents
insurance, health, reimbursement
irbesartan
biphenyl compounds
tetrazoles
evaluation of the transparency committee
Irbesartan

---
http://www.has-sante.fr/portail/display.jsp?id=c_399417
2002
France
French
drug combinations
sodium chloride symporter inhibitors
antihypertensive agents
diuretics
hydrochlorothiazide
tablets
angiotensin II type 1 receptor blockers
irbesartan and diuretics
evaluation of the transparency committee
Irbesartan
biphenyl compounds
tetrazoles

---
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08/06/2024


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