Hypoxanthine - CISMeF

Preferred Label : Hypoxanthine;

NCIt synonyms : 1,7-Dihydro-6H-purin-6-one;

NCIt definition : A purine-based organic compound in human muscle tissues, Hypoxanthine is formed during purine catabolism as a product of xanthine oxidase action on xanthine, and occasionally is found as a constituent of nucleic acids. The potent anti-inflammatory and cytoprotective effects of purines may be mediated by cell surface adenosine receptors. Hypoxanthine protects against oxidant-induced cell injury by inhibiting activation of nuclear poly(ADP-ribose) polymerase (PARP). (NCI04);

UNII : 2TN51YD919;

InChIKey : FDGQSTZJBFJUBT-UHFFFAOYSA-N;

CAS number : 68-94-0;

Chemical formula : C5H4N4O;

NSC code : 14665;

ChEBI ID : CHEBI:17368;

Codes from synonyms : 30508;

PubMed : 17055069;

Details

Origin ID

C29105;

UMLS CUI

C0020684;

Currated CISMeF NLP mapping
- Hypoxanthine [LOINC component]
- Hypoxanthine (substance) [SNOMED CT concept]
- hypoxanthine [MeSH concept]
- hypoxanthine [SNOMED Notion]
- hypoxanthine [MeSH Descriptor]
- hypoxanthines [MeSH Descriptor]
- hypoxanthines [MeSH concept]
- purin-6(1h)-one [Substance BNPC]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Hypoxanthine [LOINC component]
- Hypoxanthine (substance) [SNOMED CT concept]
- hypoxanthine [SNOMED Notion]
- hypoxanthine [MeSH concept]
- hypoxanthine [MeSH Descriptor]
chemical_or_drug_affects_gene_product
- Poly [ADP-Ribose] Polymerase 1 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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