Desipramine Hydrochloride

Preferred Label : Desipramine Hydrochloride;

NCIt definition : The hydrochloride salt form of desipramine, a secondary amine tricyclic antidepressant (TCA). In the central nervous system (CNS), desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.;

UNII : 1Y58DO4MY1;

InChIKey : XAEWZDYWZHIUCT-UHFFFAOYSA-N;

CAS number : 58-28-6;

Drug name : Norpramin; Pertofrane;

Chemical formula : C18H22N2.HCl;

NSC code : 114901;

ChEBI ID : CHEBI:4449;

Details

Origin ID

C28979;

UMLS CUI

C0700529;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Desipramine Hydrochloride [MeSH concept]
- Desipramine hydrochloride [Substance BNPC]
- Desipramine hydrochloride (substance) [SNOMED CT concept]
- desipramine hydrochloride [SNOMED Notion]
Validated automatic mappings to NTBT
- desipramine [MeSH Descriptor]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Desipramine [NCIt concept]
is_salt_form_of
- Desipramine [NCIt concept]

Keyword's position in hierarchy(ies) :

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