Desipramine - CISMeF

Preferred Label : Desipramine;

NCIt definition : An active metabolite of imipramine, a tertiary amine and a synthetic tricyclic derivative of the antidepressant. Desipramine enhances monoamine neurotransmission in certain areas of the brain by inhibiting the re-uptake of noradrenaline and serotonin at the noradrenergic and serotoninergic nerve endings, respectively. It also induces sedation through histamine 1 receptor blockage and hypotension through beta-adrenergic blockage.;

UNII : TG537D343B;

InChIKey : HCYAFALTSJYZDH-UHFFFAOYSA-N;

CAS number : 50-47-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 50-47-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C18H22N2;

ChEBI ID : CHEBI:47781;

Codes from synonyms : 30353;

Details

Origin ID

C61700;

UMLS CUI

C0011685;

Automatic exact mappings (from CISMeF team)
- Desipramine [ICHI extension code]
- desipramine [medical devices type]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Desipramine [ICD-11 Extension code]
- Desipramine [LOINC component]
- Desipramine (substance) [SNOMED CT concept]
- Product containing desipramine (medicinal product) [SNOMED CT concept]
- desipramine [ATC Code]
- desipramine [Substance BNPC]
- desipramine [MeSH concept]
- desipramine [MeSH Descriptor]
- desipramine [SNOMED Notion]
Validated automatic mappings to BTNT
- desipramine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Desipramine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Desipramine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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