" /> Desipramine - CISMeF





Preferred Label : Desipramine;

NCIt definition : An active metabolite of imipramine, a tertiary amine and a synthetic tricyclic derivative of the antidepressant. Desipramine enhances monoamine neurotransmission in certain areas of the brain by inhibiting the re-uptake of noradrenaline and serotonin at the noradrenergic and serotoninergic nerve endings, respectively. It also induces sedation through histamine 1 receptor blockage and hypotension through beta-adrenergic blockage.;

UNII : TG537D343B;

InChIKey : HCYAFALTSJYZDH-UHFFFAOYSA-N;

CAS number : 50-47-5;

Chemical formula : C18H22N2;

ChEBI ID : CHEBI:47781;

Codes from synonyms : 30353;

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10/05/2025


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