" /> Benazepril Hydrochloride - CISMeF





Preferred Label : Benazepril Hydrochloride;

NCIt synonyms : Benazepril HCl;

NCIt definition : The hydrochloride salt of benazepril, a carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : N1SN99T69T;

InChIKey : VPSRQEHTHIMDQM-FKLPMGAJSA-N;

CAS number : 86541-74-4;

Drug name : Lotensin;

Molecule name : CGS14824A;

Chemical formula : C24H28N2O5.ClH;

Codes from synonyms : 32055;

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31/05/2025


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