" /> Benazepril - CISMeF





Preferred Label : Benazepril;

NCIt definition : A carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : UDM7Q7QWP8;

InChIKey : XPCFTKFZXHTYIP-PMACEKPBSA-N;

CAS number : 86541-75-5;

Chemical formula : C24H28N2O5;

ChEBI ID : CHEBI:3011;

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08/05/2025


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