NCIt definition : A recombinant peptide consisting of amino acid residues 180 to 188 of the tyrosinase-related
protein 2 (TRP2). Expressed by cells of melanocyte origin, TRP2 is an enzyme involved
in the process that converts tyrosinase to melanin pigments. Vaccination with TRP-2:
180-188 peptide may induce cytotoxic T lymphocyte (CTL) responses to melanoma cells.
(NCI04);