NCIt definition : A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived
from the canarypox virus. ALVAC-B7-CEA expresses carcinoembryonic antigen (CEA), a
protein that is overexpressed by many tumor cells, and B7.1 (also known as CD80),
the natural ligand for the T-cell antigen CD28, to augment the host immune response.
This agent has been shown to stimulate a host immune response against tumor cells
that express CEA. (NCI04);