NCIt synonyms : Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor; Ewing's Family of Tumours; Ewing Family of Tumors; Ewing's Family of Tumors; Tumors of the Ewing's Family; Tumors of Ewing's Family; Ewing s Sarcoma Peripheral Primitive Neuroectodermal Tumor;
NCIt related terms : Ewing sarcoma/Peripheral PNET; EFTs; Ewing sarcoma family of tumors;
NCIt definition : A spectrum of malignant tumors, affecting mostly males under age 20, characterized
morphologically by the presence of small round cells. Ewing sarcoma and peripheral
primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma
lacking evidence of neural differentiation and the markers that characterize the peripheral
primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal
tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture
and immunohistochemical abnormalities. These tumors may occur in the soft tissues
or the bones. Pain and the presence of a mass are the most common clinical symptoms.;
Alternative definition : NCI-GLOSS: A group of cancers that includes Ewing tumor of bone (ETB or Ewing sarcoma
of bone), extraosseous Ewing (EOE) tumors, primitive neuroectodermal tumors (PNET
or peripheral neuroepithelioma), and Askin tumors (PNET of the chest wall). These
tumors all come from the same type of stem cell.;
Neoplastic status : Malignant;
Codes from synonyms : 10015563; CDR0000570758; CDR0000322134;