EWSR1/FLI1 Fusion Gene Type 1

Preferred Label : EWSR1/FLI1 Fusion Gene Type 1;

NCIt synonyms : EWSR1-FLI1 Fusion Gene Type 1; EWS/FLI1 Fusion Gene Type 1; EWS-FLI1 Fusion Gene Type 1; EWSR1::FLI1 Fusion Gene Type 1;

NCIt definition : A fusion gene ( 4.1 kb) that results from a chromosomal translocation t(11;22)(q24;q12) which fuses the first seven exons of the EWSR1 gene with exon 6 of the FLI1 gene. This rearrangement is associated with Ewing tumor/peripheral primitive neuroectodermal tumor.;

GenBank Accession Number : JF290489;

Details

Origin ID

C99203;

UMLS CUI

C3274604;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EWSR1/FLI1 Fusion Protein Type 1 [NCIt concept]
gene_has_abnormality
- FET Family Gene Translocation [NCIt concept]
- t(11;22)(q24;q12) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor [NCIt concept]
related_to_genetic_biomarker
- EWSR1 Gene [NCIt concept]
- FLI1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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