" /> Idronoxil - CISMeF





Preferred Label : Idronoxil;

NCIt synonyms : 3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol;

NCIt related terms : phenoxodiol;

NCIt definition : A synthetic flavonoid derivative. Idronoxil activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), and disrupts FLICE inhibitory protein (FLIP) expression, resulting in tumor cell apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex, thereby preventing DNA replication and resulting in tumor cell death.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.;

UNII : 995FT1W541;

InChIKey : ZZUBHVMHNVYXRR-UHFFFAOYSA-N;

CAS number : 81267-65-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 81267-65-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : NV-06; NOX66;

Chemical formula : C15H12O3;

Codes from synonyms : 32001; CDR0000045038;

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Keyword's position in hierarchy(ies) : arborescence

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14/05/2024


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