Homeobox Protein Hox-A10

Preferred Label : Homeobox Protein Hox-A10;

NCIt synonyms : HOX1H; HOXA10 Protein; Centaurin Alpha 1-Like; Homeobox Protein Hox-1.8; Hox-1H; HOX1.8; Homeobox Protein 1H; Homeobox Protein HOXA10; HOXA10; PL; Homeobox Protein A10; Homeobox Protein Hox-1H; Homeobox Protein-A10;

NCIt definition : Homeobox protein Hox-A10 (410 aa, 42 kDa) is encoded by the human HOXA10 gene. This protein plays a role in embryonic pattern formation.;

NCIt note : Homeobox protein Hox-A10 binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. (UniProt); Homeobox Protein A10 isoforms are inhibitory transcription factors, containing a common DNA-binding homeobox domain, that may regulate morphogenesis and differentiation by providing anterior-posterior positional identity. HOXA10 protein is also expressed in adult endometrium during early pregnancy. HOXA10 may mediate progesterone regulation of uterine EP3 and EP4. HOXA10 also appears to regulate hematopoietic lineage commitment. (from LocusLink, Swiss-Prot, OMIM);

Details

Origin ID

C26309;

UMLS CUI

C1334038;

Automatic exact mappings (from CISMeF team)
- Chorionic somatomammotropin hormone 1 [OMIM gene]
- Homeobox A10 Proteins [MeSH Descriptor]
- Homeobox A10 Proteins [MeSH concept]
- Homeobox a10 [OMIM gene]
- Hoxa10 protein, mouse [MeSH Supplementary Concept]
- Pancreatic lipase [OMIM gene]
- Papillon-lefevre syndrome [OMIM Phenotype]
- Picoliter (qualifier value) [SNOMED CT concept]
- Posterolateral auditory cortex [FMA entity]
- With (attribute) [SNOMED CT concept]
- alginate-polylysine-alginate [MeSH Supplementary Concept]
- spinal puncture [MeSH Descriptor]
OMIM relation
- Homeobox a10 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- HOXA10 protein, human [MeSH Supplementary Concept]
- HOXA10 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HOXA10 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Endometrium [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_is_element_in_pathway
- HDAC Class III Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Morphogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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