BAG Family Molecular Chaperone Regulator 5

Preferred Label : BAG Family Molecular Chaperone Regulator 5;

NCIt synonyms : BAG5; BAG-Family Molecular Chaperone Regulator-5; BAG-5; BCL2-associated Athanogene 5; BCL2-Associated Athanogene-5; Bcl-2-Associated Athanogene 5;

NCIt definition : BAG family molecular chaperone regulator 5 (447 aa, 51 kDa) is encoded by the human BAG5 gene. This protein is involved in the negative regulation of apoptosis, the inhibition of protein ubiquitination and the modulation of protein folding.;

NCIt note : BAG family molecular chaperone regulator 5 contains 4 bag domains and, when bound to HSP70/HSC70 ATPase domains, inhibits HSP70/HSC70 chaperone activity by promoting substrate release.;

Details

Origin ID

C26144;

UMLS CUI

C1565834;

OMIM relation
- Bag cochaperone 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BAG5 protein, human [MeSH Supplementary Concept]
- BAG5 protein, human [MeSH concept]
gene_encodes_gene_product
- BAG5 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of Apoptosis [NCIt concept]
- Protein Folding [NCIt concept]
- Signal Transduction [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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