Liothyronine Sodium

Preferred Label : Liothyronine Sodium;

NCIt related terms : Triostat; Cytomel;

NCIt definition : The sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).;

Alternative definition : NCI-GLOSS: A drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also being studied in the treatment of thyroid cancer. Cytomel is made in the laboratory and is a form of the thyroid hormone triiodthyronine (T3).;

UNII : GCA9VV7D2N;

InChIKey : SBXXSUDPJJJJLC-YDALLXLXSA-M;

CAS number : 55-06-1;

Drug name : Cytomel; Triostat;

Chemical formula : C15H11I3NO4.Na;

ChEBI ID : CHEBI:6484;

Codes from synonyms : CDR0000579910; CDR0000579911; CDR0000046744;

Details

Origin ID

C2581;

UMLS CUI

C0546882;

Automatic exact mappings (from CISMeF team)
- triiodothyronine [MeSH Descriptor]
CISMeF manual mappings
- Liothyronine Sodium [MeSH concept]
See also inter- (CISMeF)
- Product containing liothyronine (medicinal product) [SNOMED CT concept]
- liothyronine sodium preparation [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Liothyronine sodium (substance) [SNOMED CT concept]
- liothyronine sodium [ATC Code]
- liothyronine sodium preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- liothyronine sodium [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_free_acid_or_base_form
- Liothyronine [NCIt concept]
is_salt_form_of
- Liothyronine [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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