Liothyronine - CISMeF

Preferred Label : Liothyronine;

NCIt synonyms : L-Triiodothyronine; Triiodothyronine; Therapeutic T3; Therapeutic Triiodothyronine;

NCIt definition : A therapeutic formulation of the primary physiologically active form of endogenous thyroid hormone. In vivo, triiodothyronine enters the nucleus and binds to nuclear thyroid hormone receptors that subsequently bind to thyroid response elements (TREs) located in target genes. Receptor binding by triiodothyronine in combination with recruited coactivators results in maximal transcriptional activation after binding to TREs; in general, binding of thyroid hormone receptor alone to TREs leads to repression of gene transcription (NCI04);

UNII : 06LU7C9H1V;

InChIKey : AUYYCJSJGJYCDS-LBPRGKRZSA-N;

CAS number : 6893-02-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 6893-02-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C15H12I3NO4;

NSC code : 80203;

ChEBI ID : CHEBI:18258;

Details

Origin ID

C907;

UMLS CUI

C0041014;

Currated CISMeF NLP mapping
- Liothyronine [ICD-11 Extension code]
- Liothyronine [MeSH concept]
- Liothyronine [ICHI extension code]
- Product containing liothyronine (medicinal product) [SNOMED CT concept]
- Tri-iodothyronine [MedDRA Preferred Term]
- Triiodothyronine [LOINC component]
- triiodothyronine [Substance BNPC]
- triiodothyronine [MeSH Descriptor]
- triiodothyronine [MeSH concept]
- triiodothyronine [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Liothyronine (substance) [SNOMED CT concept]
- Product containing liothyronine (medicinal product) [SNOMED CT concept]
- Triiodothyronine [LOINC component]
- triiodothyronine [Substance BNPC]
- triiodothyronine [MeSH Descriptor]
- triiodothyronine [MeSH concept]
- triiodothyronine [SNOMED Notion]
- triiodothyronine preparation [SNOMED Notion]
Validated automatic mappings to NTBT
- Liothyronine (substance) [SNOMED CT concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_salt_form
- Liothyronine Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Liothyronine Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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