NCIt definition : A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived
from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination,
MUC-1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T
lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth
inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that
is overexpressed on the cell surfaces of many epithelial tumor cells as well as on
the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells.;