AGXT wt Allele

Preferred Label : AGXT wt Allele;

NCIt synonyms : AGT; Alanine--Glyoxylate and Serine--Pyruvate Aminotransferase Gene; Alanine--Glyoxylate Aminotransferase Gene; PH1; Primary Hyperoxaluria Type 1 Gene; Alanine-Glyoxylate Aminotransferase wt Allele; AGT1; Hepatic Peroxisomal Alanine:Glyoxylate Aminotransferase Gene; L-Alanine: Glyoxylate Aminotransferase 1 Gene; Oxalosis I Gene; Serine:Pyruvate Aminotransferase Gene; AGXT1; Ser-PyrAT; SPAT; SPT; Glycolicaciduria Gene; TLH6;

NCIt definition : Human AGXT wild-type allele is located in the vicinity of 2q37.3 and is approximately 12 kb in length. This allele, which encodes alanine-glyoxylate aminotransferase protein, is involved in gluconeogenesis, L-serine metabolism and glyoxylate detoxification. Mutations in the gene are associated with primary hyperoxaluria 1.;

GenBank Accession Number : D13368;

Détails

Origin ID

C214445;

OMIM relation
- Alanine-glyoxylate aminotransferase [OMIM gene]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- Glycine, Serine and Threonine Metabolism Pathway [NCIt concept]
- Glyoxylate and Dicarboxylate Metabolism Pathway [NCIt concept]
- Peroxisome Biogenesis Pathway [NCIt concept]
gene_plays_role_in_process
- Amino Acid Metabolic Process [NCIt concept]
- Detoxification [NCIt concept]
- Gluconeogenic Process [NCIt concept]

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