Protein Salvador Homolog 1

Preferred Label : Protein Salvador Homolog 1;

NCIt synonyms : 45 kDa WW Domain Protein; Salvador Family WW Domain Containing Protein 1; WW Domain-Containing Adaptor 45; SAV1; hWW45;

NCIt definition : Protein salvador homolog 1 (383 aa, 45 kDa) is encoded by the human SAV1 gene. This protein is involved in the activation of mammalian sterile 20-like (MST) family kinases and the promotion of promotes cell-cycle exit and terminal cell differentiation.;

Details

Origin ID

C212958;

OMIM relation
- Salvador family, ww domain-containing protein 1 [OMIM gene]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- SAV1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
gene_product_is_element_in_pathway
- Hippo Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

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