Autologous Anti-CD22 CAR-T Cells CLIC-2201

Preferred Label : Autologous Anti-CD22 CAR-T Cells CLIC-2201;

NCIt synonyms : Autologous CD22-targeting CAR T-cells CLIC-2201; Autologous Anti-CD22 CAR T Cells CLIC-2201;

NCIt definition : A preparation of autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD22, with potential antineoplastic activity. Upon administration, autologous anti-CD22 CAR-T cells CLIC-2201 recognize and kill CD22-expressing tumor cells. CD22, a B-lineage-restricted, transmembrane phosphoglycoprotein, is expressed on malignant B-cells.;

Molecule name : CLIC 2201; CLIC-2201;

NCI Metathesaurus CUI : CL1928601;

Details

Origin ID

C206263;

chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- B-Cell Receptor CD22 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients