C-X-C Motif Chemokine 2

Preferred Label : C-X-C Motif Chemokine 2;

NCIt synonyms : GRO Protein, Beta; GRO2; MIP2A Protein; GRO2 Protein; GROB Protein; CXCL2; Chemokine (C-X-C motif) Ligand 2; MGSA Beta; MIP2-Alpha; Macrophage Inflammatory Protein 2-Alpha; Macrophage Inflammatory Protein-2 Alpha; Growth-Regulated Protein Beta; Gro-Beta; Melanoma Growth Stimulatory Activity Beta; Macrophage Inflammatory Protein 2, Alpha; Macrophage Inflammatory Protein 2;

NCIt definition : C-X-C motif chemokine 2 (107 aa, 11 kDa) is encoded by the human CXCL2 gene. This protein is involved in the regulation of both chemotaxis and hematopoietic stem cell proliferation.;

NCIt note : C-X-C motif chemokine 2 is cleaved into the following chain: GRO-beta(5-73) (GRO-beta-T; hematopoietic synergistic factor; HSF; SB-251353). (UniProt);

Details

Origin ID

C20474;

UMLS CUI

C0245297;

OMIM relation
- Chemokine, cxc motif, ligand 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CXCL2 protein, human [MeSH Supplementary Concept]
- CXCL2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CXC Cytokine Gene [NCIt concept]
- CXCL2 Gene [NCIt concept]
- Cytokine Gene [NCIt concept]
gene_product_has_associated_anatomy
- Central Nervous System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Chemotactic Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Maturation [NCIt concept]

Keyword's position in hierarchy(ies) :

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