NCIt synonyms : Multiciliate Differentiation and DNA Synthesis-Associated Cell Cycle Protein; Multiciliate Differentiation and DNA Synthesis Associated Cell Cycle Protein; MCIDAS; McIdas Protein; Protein Idas;
NCIt definition : Multicilin (385 aa, 42 kDa) is encoded by the human MCIDAS gene. This protein plays
a role in the transcriptional activation of genes involved in multiciliate cell differentiation.;
NCIt note : Multicilin plays a role in cell cycle regulation by forming dimers with geminin (GMNN).
Formation of this dimer reduces the association of GMNN with DNA replication factor
Cdt1 and promotes both pre-replication complex assembly and DNA replication.;