Preferred Label : Zika Virus Genome Polyprotein;
NCIt synonyms : Genome Polyprotein; Zika Virus Polyprotein; Zika Genome Polyprotein;
NCIt definition : Zika virus genome polyprotein (3419 aa, 379 kDa) is encoded by the Zika polyprotein
gene. This protein is cleaved yielding 13 non-structural viral proteins that are involved
in viral assembly, host cell binding and infection, and the replication and transcription
of the viral genome.;
NCIt note : Zika genome polyprotein is cleaved to release the following 13 viral proteins: capsid
protein C (capsid protein, core protein); protein prM (precursor membrane protein);
peptide pr (peptide precursor); small envelope protein M (matrix protein); envelope
protein E; non-structural protein 1 (NS1); non-structural protein 2A (NS2A); serine
protease subunit NS2B (flavivirin protease NS2B regulatory subunit, non-structural
protein 2B); serine protease NS3 (flavivirin protease NS3 catalytic subunit, non-structural
protein 3, EC 3.4.21.91 , EC 3.6.1.15 , EC 3.6.4.13 ); non-structural protein 4A (NS4A);
peptide 2k; non-structural protein 4B (NS4B); RNA-directed RNA polymerase NS5 (NS5;
EC 2.1.1.56, EC 2.1.1.57, EC 2.7.7.48).;
NCI Metathesaurus CUI : CL1906805;
Origin ID : C199438;
UMLS CUI : C5856933;
Semantic type(s)
- gene_encodes_gene_product
- gene_product_has_organism_source
