Nuclear Receptor Coactivator 2

Preferred Label : Nuclear Receptor Coactivator 2;

NCIt synonyms : hTIF2; NCoA-2; bHLHe75; Class E Basic Helix-Loop-Helix Protein 75; Nuclear Receptor Coactivator-2; TIF2; Transcriptional Intermediary Factor 2; Glucocorticoid Receptor-Interacting Protein-1; NCOA2; TIF2/GRIP-1; Glucocorticoid Receptor-Interacting Protein 1; p160 Steroid Receptor Coactivator 2; Glucocorticoid Receptor Interacting Protein 1;

NCIt definition : Nuclear receptor coactivator 2 (1464 aa, 159 kDa) is encoded by the human NCOA2 gene. This protein plays a role in the regulation of steroid-mediated gene transcription.;

NCIt note : Protein_Is_Physical_Part_Of: NCOA3, IKKA/B, IKBKG, CREBBP Histone Acetyltransferase Complex; Protein_Interacts_With: HIF1A, APEX, NR3C1, Steroid Superfamily Receptors, MEF2C, MYOG;

Details

Origin ID

C19888;

UMLS CUI

C1411929;

Currated CISMeF NLP mapping
- nuclear receptor coactivator 2 [MeSH Descriptor]
- nuclear receptor coactivator 2 [MeSH concept]
OMIM relation
- Nuclear receptor coactivator 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NCOA2 protein, human [MeSH concept]
- NCOA2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- NCOA2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Transcription Coactivator [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Obesity and Thermogenesis Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Retinoic Acid Receptor Family-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Fate Control [NCIt concept]
- Cell Growth [NCIt concept]
- Homeostatic Process [NCIt concept]
- Myogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients