Preferred Label : KMT2A/TET1 Fusion Protein;
NCIt synonyms : KMT2A-TET1 Fusion Protein; Histone-Lysine N-Methyltransferase 2A/Methylcytosine Dioxygenase TET1 Fusion Protein; TET1::KMT2A Fusion Protein; KMT2A::TET1 Fusion Protein; MLL-TET1 Fusion Protein; MLL-LCX Fusion Protein;
NCIt definition : A fusion protein encoded by the KMT2A/TET1 fusion gene. This protein is comprised
of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including
the AT hook DNA binding domain and the DNA methyltransferase domain, fused with the
C-terminus of the methylcytosine dioxygenase TET1 protein, including the coiled-coil
region and the nuclear localization domain that is closest to the C-terminus.;
NCI Metathesaurus CUI : CL1906319;
Origin ID : C198872;
UMLS CUI : C5855193;
Semantic type(s)
- gene_encodes_gene_product
- related_to_genetic_biomarker
