p53 Peptide Vaccine MPS-128

Preferred Label : p53 Peptide Vaccine MPS-128;

NCIt synonyms : p53:264-272 Peptide; p53 Peptide Vaccine;

NCIt definition : A peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53 gene. p53 peptide vaccine may elicit an HLA-A2.1-restricted cytotoxic T lymphocyte immune response against tumor cells that overexpress p53 protein. (NCI04);

Molecule name : PR-147; MPS-128;

NSC code : 717111;

Details

Origin ID

C1986;

UMLS CUI

C4721705;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Cellular Tumor Antigen p53 [NCIt concept]
is_component_of_chemotherapy_regimen
- Interleukin-2/p53 Peptide Vaccine [NCIt concept]
- Montanide ISA-51/p53 peptide vaccine/Sargramostim [NCIt concept]

Keyword's position in hierarchy(ies) :

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