" /> Sipuleucel-T - CISMeF





Preferred Label : Sipuleucel-T;

NCIt synonyms : PA2024 (PAP/GM-CSF)-Loaded Dendritic Cell Vaccine; APC8015 Vaccine; SipT;

NCIt related terms : APC8015; Provenge;

NCIt definition : A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP. (NCI05);

Alternative definition : NCI-GLOSS: A drug used to treat prostate cancer that has spread. It is made from immune system cells collected from a patient with prostate cancer. The cells are treated with a protein that is made by combining a protein found on prostate cancer cells with a growth factor. When the cells are injected back into the patient, they may stimulate T cells to kill prostate cancer cells. Provenge is a type of vaccine and a type of cellular adoptive immunotherapy.;

UNII : 8Q622VDR18;

CAS number : 917381-47-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 917381-47-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Provenge;

Molecule name : APC8015;

NSC code : 720270;

Codes from synonyms : CDR0000579628; CDR0000579625; CDR0000044966; 467;

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15/05/2024


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