Preferred Label : SWI1;
NCIt synonyms : Mating Type Switch 1; Switch 1; Swi1/Adr6;
NCIt definition : A component of the SWI/SNF global transcription activator complex, SWI1 acts in complex
with Snf2p, Snf5p, Snf6p, and Swi3p to assist gene-specific activators through nucleosome/chromatin
remodeling. SWI1 is involved in the regulation of many genes, including ADH1, ADH2,
GAL1, HO, INO1 and SUC2. The SWI/SNF complex is required for induced expression of
many genes and alters chromatin structure to facilitate binding of gene-specific dedicated
transcription factors. A zinc finger non-specific RNA polymerase II transcription
factor, SWI1 contains an ARID domain. (from SWISS-PROT P09547, SGD S0005937, and NCI);
Origin ID : C19807;
UMLS CUI : C1335884;
Semantic type(s)
- gene_product_has_organism_source
- gene_product_is_physical_part_of
