Recombinant Interferon Alfa-2a

Preferred Label : Recombinant Interferon Alfa-2a;

NCIt synonyms : Alpha 2 Interferon; rHuIFN-a 2a; Interferon alfa 2a; Recombinant Interferon Alpha-2a; IFN-Alpha 2; IFN alpha-2A; Interferon Alpha-2a;

NCIt related terms : INTERFERON ALFA-2A;

NCIt definition : A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04);

UNII : 47RRR83SK7;

CAS number : 76543-88-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 76543-88-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Roferon A; Laroferon; Roceron-A; Roferon-A;

NSC code : 367982;

Codes from synonyms : 274;

Details

Origin ID

C1952;

UMLS CUI

C0021734;

Automatic exact mappings (from CISMeF team)
- interferon alpha 2 [HGNC gene]
- interferon alpha-2 [MeSH concept]
- interferon, alfa 2(125-129) [MeSH concept]
- interferon, alfa 2(125-129) [MeSH Supplementary Concept]
- interferon, alpha 2(1-110) [MeSH concept]
- interferon, alpha 2(1-110) [MeSH Supplementary Concept]
- interferon, alpha 2(111-153) [MeSH concept]
- interferon, alpha 2(111-153) [MeSH Supplementary Concept]
- interferon-alpha [MeSH Descriptor]
Currated CISMeF NLP mapping
- Interferon Alfa-2a [MeSH concept]
- Interferon alfa-2a (substance) [SNOMED CT concept]
- Interferon alfa-2b (substance) [SNOMED CT concept]
- Interferon alpha-2 [MeSH Descriptor]
- Product containing interferon alfa-2a (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Interferon Alfa-2a [MeSH concept]
- Interferon alfa-2a (substance) [SNOMED CT concept]
- Interferon alpha-2 [MeSH Descriptor]
- Product containing interferon alfa-2a (medicinal product) [SNOMED CT concept]
- interferon alfa-2a [ATC Code]
Validated automatic mappings to BTNT
- interferon alfa-2a [ATC Code]
chemical_or_drug_affects_gene_product
- Interferon Alpha Receptor Complex [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Gene Regulation Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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