Tonsoku-Like Protein

Preferred Label : Tonsoku-Like Protein;

NCIt synonyms : TONSL; Tonsoku-Like DNA Repair Protein; IkappaBR; Nuclear Factor of Kappa Light Chain Gene Enhancer in B Cells Inhibitor-Like 2; Inhibitor of Kappa B-Related Protein; I-Kappa-B-Related Protein; NF-Kappa-B Inhibitor-Like Protein 2; Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor-Like 2;

NCIt definition : Tonsoku-like protein (1378 aa, 151 kDa) is encoded by the human TONSL gene. This protein is involved in the regulation of homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks.;

Details

Origin ID

C191806;

UMLS CUI

C1437915;

OMIM relation
- Tonsoku-like dna repair protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TONSL protein, human [MeSH Supplementary Concept]
- TONSL protein, human [MeSH concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- TONSL Gene [NCIt concept]
gene_product_has_associated_anatomy
- Chromosome [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
- Tetratricopeptide Repeat [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Structural Process [NCIt concept]
- DNA Repair [NCIt concept]
- Recombination Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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