t(6;14)(p21;q32)

Preferred Label : t(6;14)(p21;q32);

NCIt synonyms : t(6;14)(p21;q32) CCND3::IGH; t(6;14)(p21;q32) CCND3:IGH; t(6;14)(p21;q32) CCND3/IGH; t(6;14)(p21;q32) CCND3-IGH;

NCIt definition : A cytogenetic abnormality that refers to the translocation of the short arm (p21) of chromosome 6 and the long arm (q32) of chromosome 14. This juxtaposes the CCND3 gene with the promoter regions of the immunoglobulin heavy chain gene locus, which results in overexpression of the G1/S-specific cyclin-D3 protein.;

NCI Metathesaurus CUI : CL1904933;

Details

Origin ID

C191646;

UMLS CUI

C5784638;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 14 [NCIt concept]
- Human Chromosome 6 [NCIt concept]
is_abnormality_of_gene
- CCND3/IGH Fusion Gene [NCIt concept]
molecular_abnormality_involves_gene
- CCND3 Gene [NCIt concept]
- CCND3/IGH Fusion Gene [NCIt concept]
- Immunoglobulin Heavy Component Gene [NCIt concept]
- Immunoglobulin Heavy Locus [NCIt concept]

Keyword's position in hierarchy(ies) :

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