" /> CCND3/IGH Fusion Gene - CISMeF





Preferred Label : CCND3/IGH Fusion Gene;

NCIt synonyms : CCND3-IGH; IGH-CCND3; IGH/CCND3 Fusion Gene; CCND3-IGH Fusion Gene; IGH-CCND3 Fusion Gene; CCND3::IGH Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation, t(6;14)(p21.1;q32.3), which fuses transcriptional enhancers of the immunoglobulin heavy chain (IGH) gene locus with the 5' regulatory region of the CCND3 gene. This rearrangement is associated with multiple myeloma, diffuse large B-cell lymphoma (DLBCL) and marginal zone lymphoma.;

NCIt note : This fusion results in overexpression of the G1/S-specific cyclin-D3 protein.;

NCI Metathesaurus CUI : CL1792907;

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11/05/2025


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