A2M/ALK Fusion Protein

Preferred Label : A2M/ALK Fusion Protein;

NCIt synonyms : A2M-ALK Fusion Protein; A2M::ALK Fusion Protein; Alpha-2-Macroglobulin/ALK Tyrosine Kinase Receptor Fusion Protein; Alpha-2-Macroglobulin::ALK Tyrosine Kinase Receptor Fusion Protein;

NCIt definition : A fusion protein (680 aa, 75 kDa) that is encoded by the A2M/ALK fusion gene. This protein contains the N-terminus of the alpha-2-macroglobulin protein, including the bait region, and the transmembrane and cytoplasmic domains of the ALK tyrosine kinase receptor protein, including the tyrosine kinase domain.;

NCI Metathesaurus CUI : CL1798818;

PubMed : 24965693;

Details

Origin ID

C190103;

UMLS CUI

C5787224;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- A2M/ALK Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- A2M Gene [NCIt concept]
- ALK Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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