A2M/ALK Fusion Gene

Preferred Label : A2M/ALK Fusion Gene;

NCIt synonyms : A2M/ALK Gene Fusion; A2M-ALK Fusion Gene; A2M::ALK Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(2;12)(p23;p13) which fuses exon 22 of the A2M gene with exon 19 of the ALK gene. This fusion is associated with fetal interstitial lung tumors.;

NCIt note : Onoda, T., et.al. notes the breakpoints lie within introns 22 and 18 of A2M and ALK, respectively. (Genes Chromosomes Cancer. 2014; 10:865-74.);

NCI Metathesaurus CUI : CL1798821;

Details

Origin ID

C190102;

UMLS CUI

C5783495;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- A2M/ALK Fusion Protein [NCIt concept]
gene_mapped_to_disease
- Fetal Lung Interstitial Tumor [NCIt concept]
related_to_genetic_biomarker
- A2M Gene [NCIt concept]
- ALK Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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