SARS-CoV-2 Spike Receptor Binding Domain

Preferred Label : SARS-CoV-2 Spike Receptor Binding Domain;

NCIt synonyms : Receptor-Binding Domain; RBD; Spike Glycoprotein Receptor Binding Domain; Receptor Binding Domain; SARS-CoV-2 Spike RBD;

NCIt related terms : Receptor Binding Domain (RBD); SARS-CoV-2 S Protein RBD; SARS-COV-2 SPIKE PROTEIN RBD; SARS-CoV-2 Spike Protein Receptor-Binding Domain;

NCIt definition : A 223 amino acid domain found in the S1 subunit of the SARS-CoV-2 spike glycoprotein. This domain mediates viral particle binding to angiotensin-converting enzyme 2 on the surface of host cells.;

Alternative definition : CDISC: The region within the spike protein of the Severe Acute Respiratory Syndrome Coronavirus 2 virus (SARS-CoV-2) that enables viral binding to angiotensin-converting enzyme 2 (ACE2) receptor and fusion into the membrane of host epithelial cells.;

NCI Metathesaurus CUI : CL1793497;

Details

Origin ID

C188490;

UMLS CUI

C5703233;

Automatic exact mappings (from CISMeF team)
- receptor binding domain [COVID-19 Thesaurus concept]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- SeroNet Authorized Values [NCIt concept]
- SeroNet Study Descriptors [NCIt concept]
is_structural_domain_or_motif_of_gene_product
- SARS-CoV-2 Spike Glycoprotein [NCIt concept]
- SARS-CoV-2 Spike Protein S1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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