" /> Oblimersen - CISMeF





Preferred Label : Oblimersen;

NCIt synonyms : 5'-tct ccc agc gtg cgc cat;

NCIt related terms : olbimersen;

NCIt definition : A phosphorothioate antisense oligonucleotide. Targeted to the initiation codon region of the bcl-2 mRNA, oblimersen inhibits bcl-2 mRNA translation, resulting in decreased expression of the bcl-2 protein, an apoptotic inhibitor expressed in some types of cancer and linked to tumor drug resistance. This agent may enhance the efficacy of standard cytotoxic chemotherapy. (NCI04);

UNII : 85J5ZP6YSL;

CAS number : 190977-41-4;

Chemical formula : C172H221N62O91P17S17;

Codes from synonyms : CDR0000044355; 136048;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
30/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.