Preferred Label : MYB/QKI Fusion Protein;
NCIt synonyms : MYB-QKI Fusion Protein; Transcriptional Activator Myb-Protein Quaking Fusion Protein; Transcriptional Activator Myb/Protein Quaking Fusion Protein; MYB::QKI Fusion Protein;
NCIt definition : A fusion protein encoded by the MYB/QKI fusion gene. This protein is comprised of
the N-terminus of transcriptional activator Myb protein, including the helix-turn-helix
(HTH)-type DNA binding domain and the transactivation domain (long variants resulting
from fusions including exon 15 of the MYB gene also have a C-terminal negative regulatory
domain), which is fused to the amino acids comprising the C-terminal half of protein
quaking, which excludes the RNA binding KH domain but includes the QUA2 RNA binding
and SH3-binding domains (both the long and short variants of this fusion protein may
also include the QKI C-terminal nuclear localization sequence (NLS)).;
NCI Metathesaurus CUI : CL1773430;
PubMed : 19841262;
Origin ID : C185217;
UMLS CUI : C5669768;
Semantic type(s)
- gene_encodes_gene_product
- related_to_genetic_biomarker
