DMC1 wt Allele

Preferred Label : DMC1 wt Allele;

NCIt synonyms : DMC1H; DNA Meiotic Recombinase 1 wt Allele; DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination Gene; LIM15; DMC1 (Dosage Suppressor of Mck1, Yeast Homolog) Meiosis-Specific Homologous Recombination Gene; DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Gene; Disrupted Meiotic cDNA1, Yeast, Homolog of Gene; dJ199H16.1;

NCIt definition : Human DMC1 wild-type allele is located in the vicinity of 22q13.1 and is approximately 61 kb in length. This allele, which encodes meiotic recombination protein DMC1/LIM15 homolog protein, is involved in meiotic homologous recombination.;

NCIt note : A point mutation in the DMC1 gene was reported to be associated with non-obstructive azoospermia and premature ovarian insufficiency in one family. (Med. Genet. 2018; 55: 198-204.);

NCI Metathesaurus CUI : CL1663324;

GenBank Accession Number : D63882;

Details

Origin ID

C180694;

UMLS CUI

C5551277;

Automatic exact mappings (from CISMeF team)
- Dna meiotic recombinase 1 [OMIM gene]
OMIM relation
- Dna meiotic recombinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 22q13.1 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- DNA Repair [NCIt concept]
- Homologous Recombination [NCIt concept]
- Meiotic Recombination [NCIt concept]
- Recombination Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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