CCAAT/Enhancer Binding Protein Epsilon

Preferred Label : CCAAT/Enhancer Binding Protein Epsilon;

NCIt synonyms : CEBPE; C/EBP Epsilon; CCAAT Enhancer Binding Protein Epsilon;

NCIt definition : CCAAT/enhancer-binding protein epsilon (281 aa, 31 kDa) is encoded by the human CEBPE gene. This protein plays a role in transcriptional regulation.;

NCIt note : C/EBP epsilon is a CCAAT enhancer-binding protein and bZIP transcription factor uniquely expressed in, and essential for differentiation of, granulocytic progenitor cells. C/EBP epsilon forms homo- or heterodimers with other family members and expression is enhanced by retinoids. Four isoforms are expressed from different promoters and an alternate start codon. (OMIM);

Details

Origin ID

C17900;

UMLS CUI

C1384540;

OMIM relation
- Ccaat/enhancer-binding protein, epsilon [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CEBPE protein, human [MeSH concept]
- CEBPE protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CEBPE Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Ovary [NCIt concept]
- Peripheral Blood Mononuclear Cell [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- CCAAT Enhancer Binding Protein [NCIt concept]
- DNA Binding Protein [NCIt concept]
- Transcription Coactivator [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- bZIP Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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